Molecular Basis of Male Pattern Baldness Gene

The inheritance of baldness in males is controlled by the male pattern baldness gene which determines the presence or absence of this condition. The gene is found on the X chromosome which carries genetic information responsible for male characteristics. It has a unique arrangement of base proteins which dictate the absence or thinning of the hair in victims possessing them. This gene is found in a proximity with the androgen gene which also has a role in hair development.A variety of genes exists and some are recessive. Others are associated with multiple effects in the body. Some will code for hair baldness and influence mental development causing retardation of the normal processes. Much research is underway and subtypes of this gene are being made to try to reduce the harmful effects which affect a certain group of individuals.P2RY5 is one of the many genes which are responsible for hair loss. There exist a number of variants of this gene which exert effects which are opposite to what the original gene causes. The variants will thus increase the amount of hair produced giving a wooly appearance.A combination of these two types of this gene is being done by scientists in advanced laboratories to try to come up with a single gene which can be used in individuals affected by baldness and hair loss. This will give a lasting solution for this condition.Evolution takes place every day and this involves the specific genes coding for specific functions of the body and structure development. For the case of baldness, the gene will keep changing from one generation to another. This means that a person who is greatly affected by balding may give birth to a child who is not affected in the same way and extent. This trend may continue until a future generation emerges which does not show signs of baldness or hair loss due to weak follicles and related causes which are hereditary.Effects of these genes are experienced when the sequences of the base proteins attach to the specific receptors. Synthesis and subsequent production of hormones follow which are then transported to the hair follicles and other target regions. This sends a sign to the cells of the hair root to either stimulate hair growth or cause the muscles to shrink. Where shrinking is stimulated, the hair appears to be thin and easy to be scraped away.